Dichloromethane → 2-Methyl-2-({4-[2-(methyl{5-[4-(trifluoromethoxy)phenyl]pyrimidin-2-yl}amino)ethyl]-1,3-thiazol-2-yl}thio)propionic acid
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([C:7]([CH3:8])([S:9][c:10]1[s:11][cH:12][c:13]([CH2:15][CH2:16][N:17]([c:18]2[n:19][cH:20][c:21](-[c:24]3[cH:25][cH:26][c:27]([O:30][C:31]([F:32])([F:33])[F:34])[cH:28][cH:29]3)[cH:22][n:23]2)[CH3:35])[n:14]1)[CH3:36])=[O:37].[Cl:45][CH2:46][Cl:47].[OH:38][C:39]([C:40]([F:41])([F:42])[F:43])=[O:44]>>[O:5]=[C:6]([C:7]([CH3:8])([S:9][c:10]1[s:11][cH:12][c:13]([CH2:15][CH2:16][N:17]([c:18]2[n:19][cH:20][c:21](-[c:24]3[cH:25][cH:26][c:27]([O:30][C:31]([F:32])([F:33])[F:34])[cH:28][cH:29]3)[cH:22][n:23]2)[CH3:35])[n:14]1)[CH3:36])[OH:37]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-7a2b1376ebaa4b97a7f26ed319a3376d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…