Dimethyl Sulfoxide → N'-(4-((2-chloro-6-methyl-4-pyrimidinyl)oxy)-phenyl)-N,N-dimethylurea

HRID 320753Notes

Reaction equation

[CH3:1][OH:2].[CH3:26][S:27]([CH3:28])=[O:29].[Cl:17][c:18]1[n:19][c:20]([CH3:25])[cH:21][c:22]([Cl:24])[n:23]1.[Na:16].[OH:3][c:4]1[cH:5][cH:6][c:7]([NH:10][C:11]([N:12]([CH3:13])[CH3:14])=[O:15])[cH:8][cH:9]1>>[O:3]([c:4]1[cH:5][cH:6][c:7]([NH:10][C:11]([N:12]([CH3:13])[CH3:14])=[O:15])[cH:8][cH:9]1)[c:22]1[cH:21][c:20]([CH3:25])[n:19][c:18]([Cl:17])[n:23]1

Participants

Reactant 5

HCID 679Dimethyl Sulfoxide

HCID 887Methanol

HCID 794712,4-Dichloro-6-methylpyrimidine

HCID 3014146Urea, N'-(4-hydroxyphenyl)-N,N-dimethyl-

HCID 5360545Sodium

Product 1

HCID 21486801N'-(4-((2-chloro-6-methyl-4-pyrimidinyl)oxy)-phenyl)-N,N-dimethylurea

Sources & evidence

ORD record: ord-654d096391694726b2427222fd6ade2d
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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