Hydrochloric Acid → HCID 68931198, compound

HRID 32077Notes

Reaction equation

HRID 32077 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]([NH:13][C:14](=[O:37])[CH2:15][CH:16]([NH:23][S:24]([C:27]1[CH:36]=[CH:35][C:34]3[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=3)[CH:28]=1)(=[O:26])=[O:25])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[CH2:8][CH2:7][CH2:6]2)#[N:2].Cl>>[NH2:2][CH2:1][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]([NH:13][C:14](=[O:37])[CH2:15][CH:16]([NH:23][S:24]([C:27]1[CH:36]=[CH:35][C:34]3[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=3)[CH:28]=1)(=[O:26])=[O:25])[C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1)[CH2:8][CH2:7][CH2:6]2

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 68931881N-(6-cyano-1,2,3,4-tetrahydro-naphthalen-1-yl)-3-(naphthalen-2-yl-sulfonylamino)-3-phenyl-propionamide

Product 1

HCID 68931198HCID 68931198, compound

Procedure

The title compound was prepared from N-(6-cyano-1,2,3,4-tetrahydro-naphthalen-1-yl)-3-(naphthalen-2-yl-sulfonylamino)-3-phenyl-propionamide (Example 8, Step F) by catalytic hydrogenation and HCl salt formation as described in Example 2. MS (+ESI m/z): 514 (M+H)+.

Sources & evidence

ORD record
ord-0487785aaa2d4cb19f7f33e885fcace4
Source dataset
uspto-grants-2008_09
Patent number
US07425631B2

Reaction notes

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