Dichloromethane → 4-Nitro-benzoic acid 5-(1-ethoxycarbonyl-2-vinyl-cyclopropylcarbamoyl)-pyrrolidin-3-yl ester

HRID 320820Notes

Reaction equation

HRID 320820 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH:9]([C:25]([NH:26][C:27]2([C:32](=[O:33])[O:34][CH2:35][CH3:36])[CH:28]([CH:30]=[CH2:31])[CH2:29]2)=[O:37])[CH2:10][CH:11]([O:13][C:14]([c:15]2[cH:16][cH:17][c:18]([N+:21](=[O:22])[O-:23])[cH:19][cH:20]2)=[O:24])[CH2:12]1)([CH3:5])([CH3:6])[CH3:7].[Cl:46][CH2:47][Cl:48].[F:38][C:39]([F:40])([F:41])[S:42]([OH:43])(=[O:44])=[O:45]>>[NH:8]1[CH:9]([C:25]([NH:26][C:27]2([C:32](=[O:33])[O:34][CH2:35][CH3:36])[CH:28]([CH:30]=[CH2:31])[CH2:29]2)=[O:37])[CH2:10][CH:11]([O:13][C:14]([c:15]2[cH:16][cH:17][c:18]([N+:21](=[O:22])[O-:23])[cH:19][cH:20]2)=[O:24])[CH2:12]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 62406Trifluoromethanesulfonic acidHCID 668707382-(1-Ethoxycarbonyl-2-vinyl-cyclopropylcarbamoyl)-4-(4-nitro-benzoyloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 668708334-Nitro-benzoic acid 5-(1-ethoxycarbonyl-2-vinyl-cyclopropylcarbamoyl)-pyrrolidin-3-yl ester

Sources & evidence

ORD record
ord-fc22bf754ee84c2396a1106bf49d2c67
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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