Imidazole → 2-[3-(Tert-butyldimethylsilanyloxy)-4,4,4-trifluorobutyl]pyridine
Reaction equation
[C:15]([CH3:16])([CH3:17])([CH3:18])[Si:19]([CH3:20])([CH3:21])[Cl:22].[CH3:31][N:32]([CH3:33])[c:34]1[cH:35][cH:36][n:37][cH:38][cH:39]1.[Cl:28][CH2:29][Cl:30].[F:1][C:2]([CH:3]([CH2:4][CH2:5][c:6]1[n:7][cH:8][cH:9][cH:10][cH:11]1)[OH:12])([F:13])[F:14].[nH:23]1[cH:24][cH:25][n:26][cH:27]1>>[F:1][C:2]([CH:3]([CH2:4][CH2:5][c:6]1[n:7][cH:8][cH:9][cH:10][cH:11]1)[O:12][Si:19]([C:15]([CH3:16])([CH3:17])[CH3:18])([CH3:20])[CH3:21])([F:13])[F:14]Participants
6
Sources & evidence
- ORD record
- ord-6fa247ca009c428aae0deda283a7e87c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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