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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 321925Generated: October 27, 2026

5-Amino-2-methoxyphenol → 1,3-Dichloro-2,4,6-trifluoro-5-[(3-hydroxy-4-methoxyphenyl)aminosulfonyl]benzene

https://huagongshe.com/reaction/321925

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Amino-2-methoxyphenolHCID 74314—
Reactant3,5-Dichloro-2,4,6-trifluorophenylsulfonyl chlorideHCID 15550641—
Product1,3-Dichloro-2,4,6-trifluoro-5-[(3-hydroxy-4-methoxyphenyl)aminosulfonyl]benzeneHCID 9865817—

Reaction Steps

The title compound was prepared in a manner similar to that described in Example 6 of WO 97/3-677, beginning with 3-hydroxy4-methoxyaniline and 3,5-dichloro-2,4,6-trifluorophenylsulfonyl chloride (Example A, above).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06211167B1
Source datasetuspto-grants-2001_04
ORD IDord-38f57edbfcc04f3d925488c3b71ab347
Source noteuspto-grants-2001_04