Dichloromethane → HCID 15434936, compound

HRID 321981Notes

Reaction equation

HRID 321981 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:14](=[O:15])[NH:13][C:12](=O)[CH:11]=[N:10]2)[CH:5]=[C:6]([Cl:8])[CH:7]=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[Cl:36]CCl>>[Cl:36][C:12]1[CH:11]=[N:10][N:9]([C:4]2[CH:3]=[C:2]([Cl:1])[CH:7]=[C:6]([Cl:8])[CH:5]=2)[C:14](=[O:15])[N:13]=1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 11776TriphenylphosphineHCID 3662569HCID 3662569, compound

Product 1

HCID 15434936HCID 15434936, compound

Procedure

In 30 ml of dichloromethane suspended with 1.00 g of 2-(3,5-dichlorophenyl)-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione followed by addition of 2-fold morlar each of carbone tetrachloride and triphenylphosphine and refluxed for 12 hours. After the completion of the reaction, the resulted solution were purified by colomun chlomatography (Merck Silica Gel 60 dichloromethane-carbontetrachloride=2:1). m.p. 148-149° C.

Workup

  1. temperaturerefluxed for 12 hours
  2. customAfter the completion of the reaction
  3. customthe resulted solution were purified by colomun chlomatography (Merck Silica Gel 60 dichloromethane-carbontetrachloride=2:1)

Sources & evidence

ORD record
ord-41b59a05dfb6471c845cd0310aafe569
Source dataset
uspto-grants-2001_04
Patent number
US06211178B1

Reaction notes

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