HCID 54512153, compound → HCID 22008532, compound

HRID 321991Notes

Reaction equation

HRID 321991 reaction equation
[CH:1](=[N:8][N:9]([C:21]1[CH:26]=[C:25]([Cl:27])[C:24]([CH2:28][C:29]2[CH:34]=[CH:33][C:32]([Cl:35])=[CH:31][CH:30]=2)=[C:23]([Cl:36])[CH:22]=1)[C:10]([NH:12][CH2:13]C(OCC)OCC)=[O:11])C1C=CC=CC=1>C(#N)C.Cl>[Cl:27][C:25]1[CH:26]=[C:21]([N:9]2[C:10](=[O:11])[NH:12][CH2:13][CH:1]=[N:8]2)[CH:22]=[C:23]([Cl:36])[C:24]=1[CH2:28][C:29]1[CH:34]=[CH:33][C:32]([Cl:35])=[CH:31][CH:30]=1

Participants

4

Reactant 1

HCID 54512153HCID 54512153, compound

Product 1

HCID 22008532HCID 22008532, compoundYield 95%

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidCatalystHCID 6342AcetonitrileSolvent

Procedure

In 5 ml of acetonitrile was dissolved 0.4 g of 1-benzylidene-2-[4-(4-chlorobenzyl)-3,5-dichlorophenyl]-4-(2,2-diethoxyethyl)-semicarbazide. To the solution was added one drop of 35% hydrochloric acid. The mixture was stirred for one hour at room temperature. The reaction mixture was cooled, then resulting crystalline precipitate of the titled compound was collected by filtration. The yield was 95%. m.p.199-200° C.

Workup

  1. temperatureThe reaction mixture was cooled
  2. filtrationresulting crystalline precipitate of the titled compound was collected by filtration

Sources & evidence

ORD record
ord-8e77f65417904bfabe8315b4f7ddf77b
Source dataset
uspto-grants-2001_04
Patent number
US06211178B1

Reaction notes

Loading…