Hydrochloric Acid → Methyl 2-chloro-3-methyl-4-methylsulfonylbenzoate

HRID 322052Notes

Reaction equation

HRID 322052 reaction equation
[Cl:1][C:2]1[C:10]([CH3:11])=[C:9]([S:12]([CH3:15])(=[O:14])=[O:13])[CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].Cl.[CH3:17]O>>[Cl:1][C:2]1[C:10]([CH3:11])=[C:9]([S:12]([CH3:15])(=[O:14])=[O:13])[CH:8]=[CH:7][C:3]=1[C:4]([O:6][CH3:17])=[O:5]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 142544762-Chloro-3-methyl-4-(methylsulfonyl)benzoic acid

Product 1

HCID 15132838Methyl 2-chloro-3-methyl-4-methylsulfonylbenzoate

Procedure

53.02 g (0.21 mol) of 2-chloro-3-methyl-4-methylsulfonylbenzoic acid were dissolved in 400 ml of methanol and HCl was passed in at reflux temperature for 3 h. The mixture was then allowed to cool and completely concentrated on a rotary evaporator.

Workup

  1. temperatureat reflux temperature for 3 h
  2. temperatureto cool
  3. concentrationcompletely concentrated on a rotary evaporator

Sources & evidence

ORD record
ord-e8611f4b11d0482ca589f93782434add
Source dataset
uspto-grants-2001_04
Patent number
US06211216B1

Reaction notes

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