HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Proline → HCID 86756579, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Proline | HCID 145742 | — |
| Reactant | 3-Pyridinecarboxaldehyde, 2-amino- | HCID 737633 | — |
| Reactant | HCID 86756578 | HCID 86756578 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 86756579 | HCID 86756579 | — |
Reaction Steps
To a solution of 4-6 (12 g, 40 mmol), 2-amino-3-formylpyridine (6.3 g, 52 mmol), proline (4.6 g, 40 mmol) and ethanol (300 mL) was heated at reflux for 15 h. After cooling and evaporation, the residue was chromatographed (silica gel, 1:1 chloroform/ethyl acetate) to give 4-7 as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06211191B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-342e9c10c45243bf9f573731b2761e82 |
| Source note | uspto-grants-2001_04 |