Methyl Isocyanate → HCID 44358238, compound

Participants

Reaction Steps

(R)-N-(2,3-Dihydrobenzofuran-4-yl)-3-(amino)pyrrolidine (0.1 mmol) was dissolved in CH2Cl2 and methyl isocyanate (0.12 mmol) was added. The reaction was stirred at room temperature for 1 hour. The solvents were removed in vacuo, and the compound purified by flash chromatography eluting with 10% methanol in ethyl acetate to give 130 mg (98%) of the desired product as a solid.

Provenance & Evidence