Hydracrylonitrile → HCID 23004047, compound

HRID 322132Notes

Reaction equation

HRID 322132 reaction equation
[O:1]=[C:2]([CH2:9][CH2:10][CH3:11])[CH2:3][C:4]([O:6][CH2:7][CH3:8])=[O:5].OCC[C:15]#[N:16]>>[O:1]=[C:2]([CH2:9][CH2:10][CH3:11])[CH2:3][C:4]([O:6][CH2:7][CH2:8][C:15]#[N:16])=[O:5]

Participants

3

Reactant 2

HCID 8011HydracrylonitrileHCID 238498Ethyl 3-oxohexanoate

Product 1

HCID 23004047HCID 23004047, compound

Conditions

Temperature
192.5 °C

Procedure

A mixture of ethyl 3-oxohexanoate (33.7 mmol) and 3-hydroxypropionitrile (28.1 mmol) were placed in a round bottom flask (magnetically stirred) equipped with a short distillation path. The resulting mixture was gradually heated to 180-205° C. in an oil bath. The distillate was collected. The mixture was then cooled to room temperature and the residue was distilled under reduced pressure to give 2-cyanoethyl 3-oxohexanoate.

Workup

  1. customwere placed in a round bottom flask
  2. customequipped with a short distillation path
  3. distillationThe distillate was collected
  4. temperatureThe mixture was then cooled to room temperature
  5. distillationthe residue was distilled under reduced pressure

Sources & evidence

ORD record
ord-95cbc82a967d4ff1a8d83a3812a54b73
Source dataset
uspto-grants-2001_04
Patent number
US06211198B1

Reaction notes

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