Methanesulfonyl chloride → HCID 13079701, compound

HRID 322249Notes

Reaction equation

HRID 322249 reaction equation
[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][CH2:17][OH:18])=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:19][S:20](Cl)(=[O:22])=[O:21]>>[CH3:19][S:20]([O:18][CH2:17][CH2:16][CH2:15][C:12]1[CH:11]=[CH:10][C:9]([O:8][CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)=[CH:14][CH:13]=1)(=[O:22])=[O:21]

Participants

3

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 27640763-[4-(Benzyloxy)phenyl]propan-1-ol

Product 1

HCID 13079701HCID 13079701, compoundYield 98%

Procedure

In substantially the same manner as in Reference Example 12, 3-(4-benzyloxyphenyl)propanol was allowed to react with methanesulfonyl chloride to give 3-(4-benzyloxyphenyl)propyl methanesulfonate. The yield was 98%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 74-75° C.

Sources & evidence

ORD record
ord-d59ab3bf40164379b203e3c0417672ed
Source dataset
uspto-grants-2001_04
Patent number
US06211215B1

Reaction notes

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