HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzeneacetamide → 2-Benzyl-4-(chloromethyl)-1,3-oxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzeneacetamide | HCID 7680 | — |
| Reactant | 1,3-Dichloroacetone | HCID 10793 | — |
| Product | 2-Benzyl-4-(chloromethyl)-1,3-oxazole | HCID 22009602 | 33% |
Reaction Steps
In substantially the same manner as in Reference Example 31, phenylacetamide was allowed to react with 1,3-dichloroacetone to give 2-benzyl-4-chloromethyl oxazole. The yield was 33%. Recrystallization from hexane gave colorless prisms, mp 31-32° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06211215B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-e2433385d9a54ad9a35d07a239e0d90d |
| Source note | uspto-grants-2001_04 |