反应详情

In substantially the same manner as in Reference Example 31, 3,5-dimethoxybenzamide was allowed to react with 1,3-dichloroacetone to give 4-chloromethyl-2-(3,5-dimethoxyphenyl)oxazole. The yield was 59%. Recrystallization from ethyl acetate-hexane gave colorless needles, mp 85-86° C.