HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Acetate → 2-(2-Thienyl)-4-oxazolylmethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | 4-(Chloromethyl)-2-(thiophen-2-yl)-1,3-oxazole | HCID 2529531 | — |
| Product | 2-(2-Thienyl)-4-oxazolylmethanol | HCID 22009775 | 80% |
Reaction Steps
In substantially the same manner as in Reference Example 77, 4-chloromethyl-2-(2-thienyl)oxazole was allowed to react with sodium acetate, and then hydrolyzed to give 2-(2-thienyl)oxazolylmethanol. The yield was 80%. Recrystallization from ethyl acetate-hexane gave pale yellow prisms, mp 98-99° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06211215B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-9670a99650744b20a445864b075583b1 |
| Source note | uspto-grants-2001_04 |