HRID322367

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID69588

4,5-Diphenylimidazole

C15H12N2

结构：CS(=O)(=O)OCCCc1ccc(OCc2coc(/C=C/c3ccccc3)n2)cc1

HCID15521674

未命名化合物

PRODUCTS

生成物

$结构：C(=C\c1nc(COc2ccc(CCCn3cnc(-c4ccccc4)c3-c3ccccc3)cc2)co1)/c1ccccc1$

HCID22009650

未命名化合物

收率 53%

PROCEDURE

实验过程

In substantially the same manner as in Working Example 25, 3-[4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]propyl methanesulfonate was allowed to react with 4,5-diphenylimidazole to give 4-[4-[3-(4,5-diphenyl-1-imidazolyl)propyl]phenoxymethyl]-2-[(E)-2-phenylethenyl]oxazole. The yield was 53%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 137-138° C.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-cc6b7c4992ea4fd9956d53d48e82b2d4
来源数据集: uspto-grants-2001_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06211215B1
来源说明: uspto-grants-2001_04

反应 SMILES

CS(O[CH2:6][CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][C:17]2[N:18]=[C:19](/[CH:22]=[CH:23]/[C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[O:20][CH:21]=2)=[CH:11][CH:10]=1)(=O)=O.[C:30]1([C:36]2[N:37]=[CH:38][NH:39][C:40]=2[C:41]2[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=2)[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1>>[C:30]1([C:36]2[N:37]=[CH:38][N:39]([CH2:6][CH2:7][CH2:8][C:9]3[CH:10]=[CH:11][C:12]([O:15][CH2:16][C:17]4[N:18]=[C:19](/[CH:22]=[CH:23]/[C:24]5[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=5)[O:20][CH:21]=4)=[CH:13][CH:14]=3)[C:40]=2[C:41]2[CH:42]=[CH:43][CH:44]=[CH:45][CH:46]=2)[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1