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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 322417Generated: October 25, 2026

1-[4-(4-Hydroxyphenyl)butyl]imidazole → HCID 22009836, compound

https://huagongshe.com/reaction/322417

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[4-(4-Hydroxyphenyl)butyl]imidazoleHCID 22009664—
Reactant4-Chloromethyl-2-(3-methyl-2-thienyl)oxazoleHCID 22009832—
ProductHCID 22009836HCID 2200983687%

Reaction Steps

In substantially the same manner as in Working Example 72, 1-[4-(4-hydroxyphenyl)butyl]imidazole was allowed to react with 4-chloromethyl-2-(3-methyl-2-thienyl)oxazole to give 4-[4-[4-(1-imidazolyl)butyl]phenoxymethyl]-2-(3-methyl-2-thienyl)oxazole. The yield was 87%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 88-89° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06211215B1
Source datasetuspto-grants-2001_04
ORD IDord-e1eaf52b0e264eadb26e5e3450bd0815
Source noteuspto-grants-2001_04