HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22009805, compound → HCID 22009878, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22009805 | HCID 22009805 | — |
| Reactant | 1-[3-(4-Hydroxyphenyl)propyl]imidazole | HCID 22009818 | — |
| Product | HCID 22009878 | HCID 22009878 | 92% |
Reaction Steps
In substantially the same manner as in Working Example 72, 1-[3-(4-hydroxyphenyl)propyl]imidazole was allowed to react with 4-chloromethyl-2-[(E)-2-(2-thienyl)ethenyl]oxazole to give 4-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]-2-[(E)-2-(2-thienyl)ethenyl]oxazole. The yield was 92%. Recrystallization from ethyl acetate-isopropyl ether gave colorless prisms, mp 131-132° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06211215B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-831303fe411e40d99d599d19b5432739 |
| Source note | uspto-grants-2001_04 |