反应详情

In substantially the same manner as in Working Example 109, 1-[4-(4-hydroxyphenyl)butyl]imidazole was allowed to react with 4-chloromethyl-2-(2-thienyl)oxazole to give 4-[4-[4-(1-imidazolyl)butyl]phenoxymethyl]-2-(2-thienyl)oxazole. The yield was 61%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 106-107° C.