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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 322449Generated: October 28, 2026

1,3-Benzodioxole, 5-(chloromethyl)- → HCID 22009732, compound

https://huagongshe.com/reaction/322449

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-Benzodioxole, 5-(chloromethyl)-HCID 88713—
ReactantHCID 135819169HCID 135819169—
ProductHCID 22009732HCID 2200973243%

Reaction Steps

In substantially the same manner as in Working Example 131, 2-(4-hydroxyphenyl)-4-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]oxazole was allowed to react with piperonylchloride to give 4-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]-2-[4-(3,4-methylenedioxyphenylmethoxy)phenyl]oxazole. The yield was 43%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 124-125° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06211215B1
Source datasetuspto-grants-2001_04
ORD IDord-6dec2b0016204377a2050e97864b4758
Source noteuspto-grants-2001_04