HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22009685, compound → HCID 22009745, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22009685 | HCID 22009685 | — |
| Reactant | 1-[3-(4-Hydroxyphenyl)propyl]imidazole | HCID 22009818 | — |
| Product | HCID 22009745 | HCID 22009745 | 66% |
Reaction Steps
In substantially the same manner as in Working Example 146, 5-(2-thienyl)-2-thiazolylmethanol was mesylated and then reacted with 1-[3-(4-hydroxyphenyl)propyl]imidazole to obtain 2-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]-5-(2-thienyl)thiazole. The yield was 66%. Recrystallization from ethyl acetate-hexane gave orange prisms, mp 82-84° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06211215B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-a901603a62fd48c884cb7580408dd4ee |
| Source note | uspto-grants-2001_04 |