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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 322473Generated: October 30, 2026

2-(Chloromethyl)-5-(2-thienyl)oxazole → HCID 22009657, compound

https://huagongshe.com/reaction/322473

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Chloromethyl)-5-(2-thienyl)oxazoleHCID 22009705—
Reactant1-[3-(4-Hydroxyphenyl)propyl]imidazoleHCID 22009818—
ProductHCID 22009657HCID 2200965790%

Reaction Steps

In substantially the same manner as in Working Example 72, 1-[3-(4-hydroxyphenyl)propyl]imidazole was reacted with 2-chloromethyl-5-(2-thienyl)oxazole to obtain 2-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]-5-(2-thienyl)oxazole. The yield was 90%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 75-76° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06211215B1
Source datasetuspto-grants-2001_04
ORD IDord-853d756973b74d238e14069e0b9664e2
Source noteuspto-grants-2001_04