Hydrochloric Acid → HCID 70224129, compound

HRID 322518Notes

Reaction equation

HRID 322518 reaction equation
C([O:3][C:4](=[O:25])[CH2:5][N:6]1[C@H:10]([CH3:11])[CH2:9][C@H:8]([CH2:12][CH2:13][C:14]2[CH:23]=[CH:22][C:21]3[CH2:20][CH2:19][CH2:18][NH:17][C:16]=3[N:15]=2)[C:7]1=[O:24])C.[ClH:26]>>[ClH:26].[CH3:11][C@H:10]1[N:6]([CH2:5][C:4]([OH:25])=[O:3])[C:7](=[O:24])[C@@H:8]([CH2:12][CH2:13][C:14]2[CH:23]=[CH:22][C:21]3[CH2:20][CH2:19][CH2:18][NH:17][C:16]=3[N:15]=2)[CH2:9]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 53908476HCID 53908476, compound

Product 1

HCID 70224129HCID 70224129, compound

Conditions

Temperature
60 °C

Procedure

A mixture of 11-11 (185 mg, 0.5356 mmol) and 6N HCl (10 mL) was heated at 60° C. for 1 h. Evaporative removal of the solvent gave 11-12 as a yellow solid.

Workup

  1. customEvaporative removal of the solvent

Sources & evidence

ORD record
ord-79b23c974bc04d5db464efa614c51898
Source dataset
uspto-grants-2001_04
Patent number
US06211184B1

Reaction notes

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