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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 322552Generated: October 29, 2026

Trifluoroacetic acid → HCID 178427568, compound

https://huagongshe.com/reaction/322552

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 178427600HCID 178427600—
SolventDichloromethaneHCID 6344—
ProductHCID 178427568HCID 178427568—

Reaction Conditions

Temperature0 °C

Reaction Steps

To a solution of Boc—Arg(Tos)—Thiazole (300 mg, 0.6 mmol) in CH2Cl2 (10 mL) at 0° C. was added TFA (10 mL). The solution was stirred at 0° C. for 2 h. The solvent and excess TFA were evaporated to an oily residue which was used directly without further purification in Example 6.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06211154B1
Source datasetuspto-grants-2001_04
ORD IDord-78ae128fb77d4415ae2108b1f3c91d02
Source noteuspto-grants-2001_04