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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 322661Generated: October 26, 2026

o-Tolylacetic acid → 2-[(2-methylphenyl)acetamido]butyric Acid Iso-butyl Ester

https://huagongshe.com/reaction/322661

Reaction equation

Participants

RoleNameHCIDCharge
Reactanto-Tolylacetic acidHCID 69519—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(2-methylphenyl)acetamido]butyric Acid Iso-butyl EsterHCID 54573498—

Reaction Steps

Following General Procedure I′ above and using 2-methylphenylacetic acid (Aldrich) and iso-butyl 2-aninobutyrate (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06211235B1
Source datasetuspto-grants-2001_04
ORD IDord-c3fdd35d5c05495390a3ee3dc95b861d
Source noteuspto-grants-2001_04