反应详情

A solution of methyl 4-benzyloxy-2-(1-o-tolylethoxy)benzoate (2.8 g) in 15% KOH in MeOH (50 mL) is refluxed for 3 hours. The solution is evaporated, the residue treated with water, brought to pH 1 with concentrated HCl, extracted with dichloromethane. The extract is dried and evaporated to give 4-benzyloxy-2-(1-o-tolylethoxy)benzoic acid as a colourless solid, m.p. 110-113° C.

1. customThe solution is evaporated
2. additionthe residue treated with water
3. extractionextracted with dichloromethane
4. customThe extract is dried
5. customevaporated