HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → N-Phenyl-3-piperidinecarboxamide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,1-Dimethylethyl 3-[(phenylamino)carbonyl]-1-piperidinecarboxylate | HCID 18104216 | — |
| Product | N-Phenyl-3-piperidinecarboxamide hydrochloride | HCID 16303570 | 55% |
Reaction Steps
A solution of 1-t-butoxycarbonyl-3-piperidinecarboxanilide (437 mg, 1.43 mmol) and hydrochloride (1 ml, 4.00 mmol, 4N ethyl acetate) was stirred for several hours. Filtration of the precipitate gave 3-piperidinecarboxanilide hydrochloride (187 mg, 55%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427615B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-00c3107a1e1b4b18a692d37fb34de1d3 |
| Source note | uspto-grants-2008_09 |