Methanol → (1-(ethoxycarbonylmethyl)-1H-benzimidazol-2-yl)(piperidin-4-yl)amine hydriodic acid salt

Beteiligte Stoffe

Reaktionsschritte

Combine (1-(ethoxycarbonylmethyl)-1H-benzimidazol-2-yl)(1-(t-butoxycarbonyl)piperidin-4-yl)amine (0.405 g, 1.00 mmol), aqueous hydriodic acid (0.29 mL, 57%), and methanol (15 mL). Heat to reflux. After 2 hour, cool to ambient temperature and add diethyl ether (100 mL) and stir to give a solid. After 1 hour, collect the solid by filtration, dissolve in methanol and add diethyl ether (100 mL) to give a solid. Collect the solid by filtration and dry in vacuo to give the title compound.

Herkunft & Nachweise