HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (1-(2-(trifluoromethoxy)ethyl)-1H-benzimidazol-2-yl)(piperidin-4-yl)amine hydrochloric acid salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (1-(2-(trifluoromethoxy)ethyl)-1H-benzimidazol-2-yl)(1-(t-butoxycarbonyl)piperidin-4-yl)amine | HCID 22009444 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | (1-(2-(trifluoromethoxy)ethyl)-1H-benzimidazol-2-yl)(piperidin-4-yl)amine hydrochloric acid salt | HCID 22009401 | — |
Reaction Steps
Combine (1-(2-(trifluoromethoxy)ethyl)-1H-benzimidazol-2-yl)(1-(t-butoxycarbonyl)piperidin-4-yl)amine and a solution of hydrochloric acid in dioxane (10 mL, 4 M). After 1 hour, evaporate in vacuo to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06211199B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-591b74fb9754415b930082a5b6576b57 |
| Source note | uspto-grants-2001_04 |