HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl bromoacetate → HCID 70228484, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl bromoacetate | HCID 7748 | — |
| Reactant | 2-Amino-5-chloropyridine | HCID 66174 | — |
| Product | HCID 70228484 | HCID 70228484 | — |
Reaction Steps
To 2-amino-5-chloropyridine, compound 9 (Aldrich, 10 g, 0.078 mol) was added ethyl bromoacetate (30 mL, 0.269 mol) and the reaction mixture stirred at room temperature for 8 hours. The heavy white precipitate was removed by filtration and recrystallized from EtOH to yield 21.9 g (95%) yield of compound 11 as white crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06214801B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-9d421ae32d564502bf9ceb0b1d823055 |
| Source note | uspto-grants-2001_04 |