反应详情

A solution of 10 (5.7 g, 21.6 mmol), triphenylphosphine (11.3 g, 43 mmol) and water (5 ml) was heated to reflux for 24 hours. After cooling to room temperature the solvent was removed in vacuo and the residue purified by chromatography on silica gel (90:9:1 CHCl3:MeOH:NH4OH).

1. temperatureto reflux for 24 hours
2. customwas removed in vacuo
3. customthe residue purified by chromatography on silica gel (90:9:1 CHCl3:MeOH:NH4OH)