HCID 22007146, compound → HCID 22007147, compound

HRID 323786Notes

Reaction equation

HRID 323786 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:21]=[CH:22][CH:23]=1)[C:7]([NH:9][S:10]([C:13]1[CH:18]=[CH:17][C:16]([O:19][CH3:20])=[CH:15][CH:14]=1)(=[O:12])=[O:11])=[O:8])([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[CH:5]=[C:6]([CH:21]=[CH:22][CH:23]=1)[C:7]([NH:9][S:10]([C:13]1[CH:18]=[CH:17][C:16]([O:19][CH3:20])=[CH:15][CH:14]=1)(=[O:12])=[O:11])=[O:8]

Participants

4

Reactant 1

HCID 22007146HCID 22007146, compound

Product 1

HCID 22007147HCID 22007147, compoundYield 48.9%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A mixture of N-(m-Nitrobenzoyl)-4-methoxybenzenesulfonamide (920 mg, 2.87 mmol) and 100 mg of 10% Pd/C in ethanol (20 mL) was shaken under H2 (60 Psi) for 2 days at room temperature. After removing the catalyst by filtration, the filtrate was concentrated to afford 430 mg of the title compound which was used in the next reaction without further purification.

Workup

  1. customAfter removing the catalyst
  2. filtrationby filtration
  3. concentrationthe filtrate was concentrated

Sources & evidence

ORD record
ord-affcd92ba2fd4d62b467838e25c56f40
Source dataset
uspto-grants-2001_04
Patent number
US06214881B1

Reaction notes

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