反应详情

13.8 g (0.05 mol) of [2-(2-thienyl)ethylamino](2-chlorophenyl)acetonitrile, prepared according to example 1 or 2, is dissolved in 30 ml of ethanol, to the solution 40 ml of 20% aqueous hydrogen bromide solution is added. The product which precipitates within a few minutes is collected, washed with ethyl acetate and then they are dried. Weight: 14 g (78.2%), mp.: 144-145° C. The product was identified by elementary analysis, IR spectrum and 1H-NMR investigation.

1. additionis added
2. customThe product which precipitates within a few minutes
3. customis collected
4. washwashed with ethyl acetate
5. customthey are dried