HRID32395

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID23133437

未命名化合物

结构：CN1C(=O)N(CC2(CS(=O)(=O)N3CCC(Oc4ccc(Cl)cn4)CC3)NC(=O)NC2=O)C(=O)C1(C)C

HCID23133491

未命名化合物

结构：O=C1NC(=O)C(CCOCc2ccccc2)(CS(=O)(=O)Cl)N1

HCID23133535

未命名化合物

PRODUCTS

生成物

结构：O=C1NC(=O)C(CCOCc2ccccc2)(CS(=O)(=O)N2CCC(Oc3ccc(Cl)cn3)CC2)N1

HCID23133560

未命名化合物

PROCEDURE

实验过程

The title compound was prepared as described in the synthesis of 5-[({4-[(5-chloropyridin-2-yl)oxy]piperidin-1-yl}sulfonyl)methyl]-5-[(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl]imidazolidine-2,4-dione starting from 5-Chloro-2-(piperidine-4-yloxy)-pyridine hydrochloride and (2,5-dioxo-4-{2-[(phenylmethyl)oxy]ethyl}imidazolidin-4-yl)methanesulfonyl chloride.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-19cf9f219fcc4f72a7ef87e51f84041f
来源数据集: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07427631B2
来源说明: uspto-grants-2008_09

反应 SMILES

[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:8][CH:9]2[CH2:14][CH2:13][N:12]([S:15](CC3(CN4C(=O)C(C)(C)N(C)C4=O)NC(=O)NC3=O)(=[O:17])=[O:16])[CH2:11][CH2:10]2)=[N:6][CH:7]=1.Cl.ClC1C=CC(OC2CCNCC2)=NC=1.[O:52]=[C:53]1[NH:57][C:56]([CH2:68]S(Cl)(=O)=O)([CH2:58][CH2:59][O:60][CH2:61][C:62]2[CH:67]=[CH:66][CH:65]=[CH:64][CH:63]=2)[C:55](=[O:73])[NH:54]1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:8][CH:9]2[CH2:14][CH2:13][N:12]([S:15]([CH2:68][C:56]3([CH2:58][CH2:59][O:60][CH2:61][C:62]4[CH:67]=[CH:66][CH:65]=[CH:64][CH:63]=4)[NH:57][C:53](=[O:52])[NH:54][C:55]3=[O:73])(=[O:17])=[O:16])[CH2:11][CH2:10]2)=[N:6][CH:7]=1