HRID324030

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID66564

Benzoic acid, 2-(4-chlorobenzoyl)-

C14H9ClO3

结构：CCOc1cc2cc(CO)cc(-c3ccnc(NN)c3)c2cc1OCC

HCID22007332

未命名化合物

PRODUCTS

生成物

结构：CCOc1cc2cc(CO)cc(-c3ccnc(-n4nc(-c5ccc(Cl)cc5)c5ccccc5c4=O)c3)c2cc1OCC

HCID22007338

未命名化合物

收率 85.3%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID174

Ethylene glycol

C2H6O2

PROCEDURE

实验过程

1-(2-Hydrazino-4-pyridyl)-3-hydroxymethyl-6,7-diethoxynaphthalene (177 mg), 1-carboxy-2-(4-chlorophenylcarbonyl)benzene (137 mg) and ethylene glycol (1 ml) are treated in the same manner as in Example 104-(3) to give 1-[2-{4-(4-chlorophenyl)-1(2H)-phthalazinon-2-yl}-4-pyridyl]-3-hydroxymethyl-6,7-diethoxynaphthalene (247 mg), which is listed in Table 14.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-4a2ea42d454c4699b72d33f0bb05dd31
来源数据集: uspto-grants-2001_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06214996B1
来源说明: uspto-grants-2001_04

反应 SMILES

[NH:1]([C:3]1[CH:8]=[C:7]([C:9]2[C:18]3[C:13](=[CH:14][C:15]([O:22][CH2:23][CH3:24])=[C:16]([O:19][CH2:20][CH3:21])[CH:17]=3)[CH:12]=[C:11]([CH2:25][OH:26])[CH:10]=2)[CH:6]=[CH:5][N:4]=1)[NH2:2].[C:27]([C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][C:31]=1[C:36]([C:38]1[CH:43]=[CH:42][C:41]([Cl:44])=[CH:40][CH:39]=1)=O)(O)=[O:28]>C(O)CO>[Cl:44][C:41]1[CH:40]=[CH:39][C:38]([C:36]2[C:31]3[C:30](=[CH:35][CH:34]=[CH:33][CH:32]=3)[C:27](=[O:28])[N:1]([C:3]3[CH:8]=[C:7]([C:9]4[C:18]5[C:13](=[CH:14][C:15]([O:22][CH2:23][CH3:24])=[C:16]([O:19][CH2:20][CH3:21])[CH:17]=5)[CH:12]=[C:11]([CH2:25][OH:26])[CH:10]=4)[CH:6]=[CH:5][N:4]=3)[N:2]=2)=[CH:43][CH:42]=1