4-Bromo-2,6-diiodophenol → (1,1':3',1''-Terphenyl)-2'-ol, 5'-phenyl-

HRID 324065Notes

Reaction equation

HRID 324065 reaction equation
C1(CCCCCCCCNC([C:18]2[CH:19]=[C:20]([C:35]3[CH:40]=[CH:39][CH:38]=[C:37](C(F)(F)F)[CH:36]=3)[C:21]([OH:34])=[C:22](C3C=CC=C(C(F)(F)F)C=3)[CH:23]=2)=O)C=CC=CC=1.Br[C:46]1[CH:51]=[C:50](I)[C:49](O)=[C:48](I)[CH:47]=1>>[C:46]1([C:18]2[CH:23]=[C:22]([C:18]3[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=3)[C:21]([OH:34])=[C:20]([C:35]3[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=3)[CH:19]=2)[CH:51]=[CH:50][CH:49]=[CH:48][CH:47]=1

Participants

3

Reactant 2

HCID 102879224-Bromo-2,6-diiodophenolHCID 22237600N-(8-phenyl-octyl)-3,5-bis(m-trifluoromethylphenyl)4hydroxy-benzamide

Product 1

HCID 3623729(1,1':3',1''-Terphenyl)-2'-ol, 5'-phenyl-

Procedure

The title compound was prepared as a solid (0.055 g, 28%, product 2: tris-arylation) from 4-bromo-2,6-diiodophenol using the procedure to step 2 of Example 40; 1H NMR (CDCl3) δ5.45 (s, 1H), 7.27-7.57 (m, 11H), 7.62 (d, J=8.3 Hz, 6H).

Sources & evidence

ORD record
ord-4111e891bc844be3b6f1cee23bb66380
Source dataset
uspto-grants-2001_04
Patent number
US06214877B1

Reaction notes

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