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HRID32407

反应详情

EQUATION

反应方程式

HRID 32407 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1ccc2c(Cl)c[nH]c2c1
HCID15543042

未命名化合物

结构：CC(C)(C)OC(=O)N1CCC(COCC(N)c2ccccn2)CC1
HCID69313232

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CCC(COCC(NC(=O)c2ccc3c(Cl)c[nH]c3c2)c2ccccn2)CC1
HCID69309680

未命名化合物

PROCEDURE

实验过程

Using coupling method A, 4-[2-amino-2-(2-pyridinyl)-ethoxymethyl]piperidine-1-carboxylic acid tert-butyl ester (730 mg, 2.2 mmol) and 3-chloroindole-6-carboxylic acid (468 mg, 2.4 mmol) afforded, after purification (SiO2: 10 DCM:2 EtOAc:2 Hexane:0 to 1.5 isopropyl amine), 835 mg (64%) of the title compound.

WORKUP

后处理

  1. customafforded
  2. customafter purification (SiO2: 10 DCM:2 EtOAc:2 Hexane:0 to 1.5 isopropyl amine), 835 mg (64%) of the title compound