HuagongsheHuagongshe Chemistry Print Report · For research reference only
Anisole → HCID 9866338, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Anisole | HCID 7519 | — |
| Reactant | 4-{(R)-2-[(3-Chloro-1H-indole-6-carbonyl)amino]-2-phenyl-ethoxymethyl}piperidine-1-carboxylic acid tert-butyl ester | HCID 69310754 | — |
| Product | HCID 9866338 | HCID 9866338 | 135.3% |
Reaction Steps
Using deprotection method B, but without addition of anisole, 4-{(R)-2-[(3-chloro-1H-indole-6-carbonyl)amino]-2-phenylethoxymethyl}piperidine-1-carboxylic acid tert-butyl ester (4.6 g crude, 8.97 mmol) afforded 5 g (100%) of the title compound as a crude residue, which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427632B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-6a087676589342d1b5145c6164696bee |
| Source note | uspto-grants-2008_09 |