HCID 20645779, compound → HCID 20645780, compound

HRID 324153Notes

Reaction equation

HRID 324153 reaction equation
[CH3:1][C@H:2]([C:11]([O:13][C:14]1[CH:19]=[CH:18][C:17]([O:20]CC2C=CC=CC=2)=[CH:16][CH:15]=1)=[O:12])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]>[Pd].C(OCC)(=O)C>[CH3:1][C@H:2]([C:11]([O:13][C:14]1[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][CH:15]=1)=[O:12])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

Participants

4

Reactant 1

HCID 20645779HCID 20645779, compound

Product 1

HCID 20645780HCID 20645780, compoundYield 88.2%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

{circle around (2)}: A mixture comprising 3.0 g of (S)-4-(1′-methylnonylcarbonyloxy)-1-benzyloxybenzene, 0.3 g of palladium/carbon and 20 g of ethyl acetate was stirred for 6 hours under hydrogen atmosphere. Then, palladium/carbon was filtered off, followed by distilling off ethyl acetate from the filtrate, whereby 2.0 g of (S)-4-(1′-methylnonylcarbonyloxy)phenol was obtained in the form of a colorless oily substance.

Workup

  1. filtrationThen, palladium/carbon was filtered off
  2. distillationby distilling off ethyl acetate from the filtrate

Sources & evidence

ORD record
ord-ea48f83569154337a59b3c5ef730f386
Source dataset
uspto-grants-2001_04
Patent number
US06217793B1

Reaction notes

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