HCID 70114158, compound → HCID 70133637, compound

HRID 324418Notes

Reaction equation

HRID 324418 reaction equation
CC(C)([O:4][C:5]1[N:10]=[C:9]([O:11]C(C)(C)C)[C:8]([C:16]2([OH:33])[C:22]3[N:23]=[C:24]([CH3:26])[S:25][C:21]=3[CH2:20][CH2:19][C:18]3[CH:27]=[C:28]([CH2:31][CH3:32])[CH:29]=[CH:30][C:17]2=3)=[CH:7][N:6]=1)C>C(O)(=O)C>[CH2:31]([C:28]1[CH:29]=[CH:30][C:17]2[C:16]([C:8]3[C:9](=[O:11])[NH:10][C:5](=[O:4])[NH:6][CH:7]=3)([OH:33])[C:22]3[N:23]=[C:24]([CH3:26])[S:25][C:21]=3[CH2:20][CH2:19][C:18]=2[CH:27]=1)[CH3:32]

Participants

3

Reactant 1

HCID 70114158HCID 70114158, compound

Product 1

HCID 70133637HCID 70133637, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of the product from step (ii) (0.44 g) in glacial acetic acid (10 ml) was stirred at room temperature overnight. The reaction mixture was evaporated to dryness (azeotroped twice with toluene) and the residue triturated with diethyl ether to give a pink solid.

Workup

  1. customThe reaction mixture was evaporated to dryness (
  2. customazeotroped twice with toluene) and the residue
  3. customtriturated with diethyl ether
  4. customto give a pink solid

Sources & evidence

ORD record
ord-df4ab8303eb04a5c9bc815ebe838eeb7
Source dataset
uspto-grants-2001_04
Patent number
US06218376B1

Reaction notes

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