4-Methoxybenzylamine → 2-Methyl-1-(4-methoxyphenylmethyl)-4H-benzo[5,6]cyclohepta[1,2-d]imidazol-4-one

Participants

Role	Name	HCID	Charge
Reactant	4-Methoxybenzylamine	HCID 75452	—
Reactant	2-Methyl-4H-benzo[5,6]cyclohepta[1,2-d]oxazol-4-one	HCID 22003576	—
Product	2-Methyl-1-(4-methoxyphenylmethyl)-4H-benzo[5,6]cyclohepta[1,2-d]imidazol-4-one	HCID 22003592	—

Reaction Conditions

Temperature	100 °C

Reaction Steps

A stirred mixture of the product from step (i) (5.07 g) and 4-methoxybenzylamine (12 ml) was heated at 100° C. for 24 h. The excess 4-methoxybenzylamine was distilled off under reduced pressure. The remaining residue was purified by recrystallisation from ethyl acetate to give the subtitle product as a pale yellow powder.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06218376B1
Source dataset	uspto-grants-2001_04
ORD ID	ord-02dc34383c2e4d848995064253073101
Source note	uspto-grants-2001_04