HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methyluracil → HCID 178432331, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methyluracil | HCID 12009 | — |
| Reactant | 2-Methyl-1-(4-methoxyphenylmethyl)-4H-benzo[5,6]cyclohepta[1,2-d]imidazol-4-ol | HCID 22003671 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 178432331 | HCID 178432331 | — |
Reaction Steps
A stirred solution of the product from step (iii) (0.819 g) in trifluoroacetic acid (20 ml) was heated at reflux for 1 h. 1-Methyluracil (0.311 g) was added and the reflux continued for 5 days. The solvent was evaporated under reduced pressure. The residue was purified by chromatography eluting with 10% methanol in dichloromethane to give the subtitle product as pale green glass.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06218376B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-a866e5d4415144668ea8de1cb16098af |
| Source note | uspto-grants-2001_04 |