HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methyluracil → (+/-)-5-(2,7-Dichloro-4H-benzo[5,6]cyclohepta[1,2-d]thiazol-4-yl)-1-methyl-2,4(1H,3H)-pyrimidinedione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methyluracil | HCID 12009 | — |
| Reactant | (+/-)-2,7-Dichloro-4H-benzo[5,6]cyclohepta[1,2-d]thiazol-4-ol | HCID 70113755 | — |
| Product | (+/-)-5-(2,7-Dichloro-4H-benzo[5,6]cyclohepta[1,2-d]thiazol-4-yl)-1-methyl-2,4(1H,3H)-pyrimidinedione | HCID 70113243 | — |
Reaction Steps
The title product was prepared from the product of step (vii) (1.27 g) and 1-methyluracil (1 g) according to the method of example 38 step (iv). Purification was by chromatography eluting with 50-60% ethyl acetate in isohexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06218376B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-744ec6c68d764b288fbf9440f9c575a7 |
| Source note | uspto-grants-2001_04 |