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HRID32450

反应详情

EQUATION

反应方程式

HRID 32450 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1ccc2c(Cl)c[nH]c2c1
HCID15543042

未命名化合物

结构：CC(C)[C@@H](N)COCC1CCN(C(C)C)CC1
HCID69310673

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)[C@H](COCC1CCN(C(C)C)CC1)NC(=O)c1ccc2c(Cl)c[nH]c2c1.Cl
HCID69309650

未命名化合物

PROCEDURE

实验过程

Using coupling method A, (R)-1-(isopropyl)-2-(1-iso-propylpiperidin-4-ylmethoxy)ethylamine (135 mg, 0.56 mmol) and 3-chloroindole-6-carboxylic acid (109 mg, 0.56 mmol) afforded, after purification (SiO2: 4:2:1 DCM:EtOAc:isopropylamine) and conversion to the HCl salt by general method A, 167 mg (66%) of the title compound.

WORKUP

后处理

  1. customafforded
  2. customafter purification (SiO2: 4:2:1 DCM:EtOAc:isopropylamine) and conversion to the HCl salt by general method A, 167 mg (66%) of the title compound