HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-1H-indole-6-carboxylic acid → HCID 69309650, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-1H-indole-6-carboxylic acid | HCID 15543042 | — |
| Reactant | HCID 69310673 | HCID 69310673 | — |
| Product | HCID 69309650 | HCID 69309650 | — |
Reaction Steps
Using coupling method A, (R)-1-(isopropyl)-2-(1-iso-propylpiperidin-4-ylmethoxy)ethylamine (135 mg, 0.56 mmol) and 3-chloroindole-6-carboxylic acid (109 mg, 0.56 mmol) afforded, after purification (SiO2: 4:2:1 DCM:EtOAc:isopropylamine) and conversion to the HCl salt by general method A, 167 mg (66%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427632B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-da8a7aa9834949d891b3a1fa2aa76cf0 |
| Source note | uspto-grants-2008_09 |