HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → N-[4-(1-Isopropylpiperidin-4-yl)-1-phenylbutyl]carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | N-[1-phenyl-4-(piperidine-4-yl)butyl]carbamic acid tert-butyl ester | HCID 69308072 | — |
| Product | N-[4-(1-Isopropylpiperidin-4-yl)-1-phenylbutyl]carbamic acid tert-butyl ester | HCID 69310736 | — |
Reaction Steps
Using alkylation method A, crude N-[1-phenyl-4-(piperidine-4-yl)butyl]carbamic acid tert-butyl ester (0.70 mmol) and acetone (1.5 mL, 20 mmol) afforded the title compound as a crude residue that was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427632B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-7252a629f6b54107b363f63d7f5a5807 |
| Source note | uspto-grants-2008_09 |