methyl 2-(benzo[1,3]dioxol-5-yl)-4-(trifluoromethanesulfonyloxy)-2H-chromen-3-carboxylate → methyl 2-(benzo[1,3]dioxol-5-yl)-4-(4-methoxy-phenyl)-2H-chromen-3-carboxylate

HRID 324589Notes

Reaction equation

HRID 324589 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6](OB(O)O)=[CH:5][CH:4]=1.[O:13]1[C:17]2[CH:18]=[CH:19][C:20]([CH:22]3[C:31]([C:32]([O:34][CH3:35])=[O:33])=[C:30](OS(C(F)(F)F)(=O)=O)[C:29]4[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=4)[O:23]3)=[CH:21][C:16]=2[O:15][CH2:14]1>>[O:13]1[C:17]2[CH:18]=[CH:19][C:20]([CH:22]3[C:31]([C:32]([O:34][CH3:35])=[O:33])=[C:30]([C:6]4[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=4)[C:29]4[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=4)[O:23]3)=[CH:21][C:16]=2[O:15][CH2:14]1

Participants

3

Reactant 2

HCID 11080999methyl 2-(benzo[1,3]dioxol-5-yl)-4-(trifluoromethanesulfonyloxy)-2H-chromen-3-carboxylateHCID 147699944-Methoxyphenyl boric acid

Product 1

HCID 11729397methyl 2-(benzo[1,3]dioxol-5-yl)-4-(4-methoxy-phenyl)-2H-chromen-3-carboxylate

Procedure

4-Methoxyphenyl boric acid and methyl 2-(benzo[1,3]dioxol-5-yl)-4-(trifluoromethanesulfonyloxy)-2H-chromen-3-carboxylate (III-5) synthesized from the compound (II-3) by a similar method as described in Reference Example 2 were reacted in a similar manner as described in Example 18 to give methyl 2-(benzo[1,3]dioxol-5-yl)-4-(4-methoxy-phenyl)-2H-chromen-3-carboxylate (Ia-4).

Workup

  1. customwere reacted in a similar manner

Sources & evidence

ORD record
ord-2b7fed30eece420e81192abb0f0f7426
Source dataset
uspto-grants-2001_04
Patent number
US06218427B1

Reaction notes

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