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HRID32461

反应详情

EQUATION

反应方程式

HRID 32461 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1ccc2c(Cl)c[nH]c2c1
HCID15543042

未命名化合物

结构：CC(C)N1CCC(CN(C)C[C@H](N)c2ccccc2)CC1.Cl.Cl
HCID69313099

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)N1CCC(CN(C)C[C@H](NC(=O)c2ccc3c(Cl)c[nH]c3c2)c2ccccc2)CC1
HCID44444046

未命名化合物

PROCEDURE

实验过程

Using coupling method A, crude (R)-N2-(1-isopropyl-piperidin-4-ylmethyl)-N2-methyl-1-phenylethane-1,2-diamine dihydrochloride (500 mg, 1.4 mmol) and 3-chloroindole-6-carboxylic acid (325 mg, 1.7 mmol) afforded, after purification (SiO2: 0 to 30% isopropylamine in 1:1 hexane:EtOAc), 115 mg (18%) of the title compound.

WORKUP

后处理

  1. customafforded
  2. customafter purification (SiO2: 0 to 30% isopropylamine in 1:1 hexane:EtOAc), 115 mg (18%) of the title compound