HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-1H-indole-6-carboxylic acid → HCID 44444046, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-1H-indole-6-carboxylic acid | HCID 15543042 | — |
| Reactant | HCID 69313099 | HCID 69313099 | — |
| Product | HCID 44444046 | HCID 44444046 | — |
Reaction Steps
Using coupling method A, crude (R)-N2-(1-isopropyl-piperidin-4-ylmethyl)-N2-methyl-1-phenylethane-1,2-diamine dihydrochloride (500 mg, 1.4 mmol) and 3-chloroindole-6-carboxylic acid (325 mg, 1.7 mmol) afforded, after purification (SiO2: 0 to 30% isopropylamine in 1:1 hexane:EtOAc), 115 mg (18%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427632B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-923545ba89784e14b2b80e305dfdf2e3 |
| Source note | uspto-grants-2008_09 |